pentobarbital will minimize the level or effect of acalabrutinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.pentobarbital will reduce the extent or effect of mifepristone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of. CYP3A4 inducers have not been researched, coadministration